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Whilst the opiate receptor relies on G protein coupling for sign transduction, this receptor was observed to benefit from arrestin activation for internalization of your receptor. Normally, the receptor promoted no other signa… Read More

Elucidating the precise pharmacological mechanism of action (MOA) of naturally occurring compounds could be demanding. Whilst Tarselli et al. (sixty) designed the first de novo artificial pathway to conolidine and showcased th… Read More

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